Synonyms: Anti-Emerin antibody produced in rabbit
MDL Number: MFCD01633315
Storage: -20C
Application: Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.Immunohistochemistry (1 paper)Western Blotting (1 paper)
Biochem Physiol Actions: EMD encodes a serine-rich nuclear membrane protein named emerin that belongs to the nuclear lamina-associated protein family. Emerin is involved in the formation of actin-based cortical network at the nuclear inner membrane. It regulates signalling pathways by interacting with ß-catenin (transcription coactivator) and controlling its flux into the nucleus. It is necessary for HIV-1 infection in the chromatin engagement by viral cDNA before integration. It is involved in the linkage of centrosome to the outer nuclear membrane.
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