Doublesex- and mab-3-related transcription factor 2 is encoded by the DMRT2 gene in human and directly regulates early activation of the myogenic determination gene MYF5 by binding in a sequence-specific manner to its early epaxial enhancer element. In addition, it is also involved in somite develoment during embryogenesis. The human protein shares a DM DNA-binding domain with Drosophila 'doublesex' (dsx) and C. elegans mab3 gene products involved in sex determination.
Synonyms: DSXL-2, Doublesex- and mab-3-related transcription factor 2, Doublesex-like 2 protein
Application: Research Sub CategoryNuclear Receptors
Other Notes: Concentration: Please refer to lot specific datasheet.