Synonyms: Anti-ATC2; Anti-CRN; Anti-Lrp4; Anti-MGC119742; Anti-TMPRSS10
Storage: -20C
Application: Anti-CORIN antibody produced in rabbit is suitable for western blotting at a concentration of 2.5mug/mL.
Biochem Physiol Actions: CORIN gene encodes for a single-pass type II membrane protein. It is a transmembrane cardiac serine protease that plays a pivotal role in converting pro-atrial natriuretic peptide to biologically active atrial natriuretic peptide that regulates blood volume and pressure. In pregnant female, it stimulates the trophoblast invasion and spiral artery remodeling in uterus. Additionally, soluble corin facilitates as a potent biomarker for heart failure (HF).