COA7 (cytochrome c oxidase 7) is a 231 amino acid-long protein present in animals. It is a putative COX (cytochrome c oxidase) assembly factor containing five sel1-like tetratricopeptide repeat sequences. It is mostly present in the mitochondrial matrix, although low levels might also be associated with the inner mitochondrial membrane.
Synonyms: Anti-C1orf163; Anti-FLJ12439; Anti-RESA1; Anti-SELRC1
Storage: -20C
Application: All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry. The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit sigma.com/prestige.
Biochem Physiol Actions: COA7 (cytochrome c oxidase 7) participates in MRC (mitochondrial respiratory chain) biogenesis. Mutations in COA7 cause mitochondrial leukoencephalopathy and inadequacy in cytochrome c oxidase.
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