Carbohydrate sulfotransferase 4 (CHST4) is an N-acetylglucosamine 6-O-sulfotransferase belonging to the novel family of carbohydrate sulfotransferases. It is highly expressed on high endothelial venules, where it is hypothesized to play an important role in lymphocyte trafficking.
Synonyms: Anti-Carbohydrate sulfotransferase 4; Anti-GST-3; Anti-GlcNAc6ST-2; Anti-HEC-GlcNAc6ST; Anti-High endothelial cells N-acetylglucosamine 6-O-sulfotransferase; Anti-LSST; Anti-N-acetylglucosamine 6-O-sulfotransferase 2
Storage: -20C
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Biochem Physiol Actions: CHST4 (Carbohydrate sulfotransferase 4) is a sulfotransferase which plays a vital role in L-selectin ligand formation in the vascular endothelial cells. It possesses GlcNAc-6-sulfotransferase activity. CHST4 transfers sulfate from 3'-phosphoadenosine 5'phospho-sulfate to the 6-hydroxyl group of N-acetylglucosamine on glycoproteins.
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