The PDGFRB (platelet derived growth factor receptor ß) gene is mapped to human chromosome 5q32. It encodes for a receptor tyrosine kinase.
Synonyms: Platelet-derived growth factor receptor beta
Storage: -20C
Biochem Physiol Actions: PDGFRB (platelet derived growth factor receptor ß) acts as a regulator of mesenchymal cells in tumour cells. Upregulation of the gene is observed in gastric cancer, breast and prostate cancers. Mutations in the gene is associated with infantile myofibromatosis.