CAMP (cationic antimicrobial peptide) is a necessary component of human innate immunity. It is also known as LL-37 (antimicrobial peptide). It is produced by various cells, including epithelial cells, keratinocytes, and neutrophils. CAMPs are designated by a- and ß-defensins and the cathelicidin-derived LL-37 peptide. It is mostly present in microenvironments, that foster carbamylation. It is located on chromosome 3p21.
Synonyms: Anti-CAP18; Anti-FALL-39; Anti-FALL39; Anti-LL37; Anti-cathelicidin antimicrobial peptide
MDL Number: MFCD08460571
Storage: -20C
Application: Anti-CAMP has been used in IF (immunofluorescence) and in immunohistochemistry.
Biochem Physiol Actions: CAMP (cationic antimicrobial peptides) kills a wide spectrum of pathogenic bacteria. It neutralizes LPS (lipopolysaccharide), and act as a chemoattractant for immune cells including T cells, monocytes, neutrophils, and mast cells. It enormously affects the direction of dendritic cell maturation, activates production of cytokines, chemokines, and their receptors and stimulates mast cell degranulation. Its major role is to act as a signaling molecule for innate and acquired immunity.
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