C19ORF66, also known as repressor of yield of dengue virus (RyDEN) , is mapped to human chromosome 19p13.2. The gene consists of eight exons spanning ~7.1kb of genomic DNA. C19ORF66 is a 291 amino acid protein, comprising eight ?-helices and seven ?-strands.
Synonyms: Anti-Chromosome 19 open reading frame 66; Anti-Flj11286
Storage: -20C
Application: Anti-C19orf66 antibody produced in rabbit has been used in fluorescent labelling.
Biochem Physiol Actions: C19ORF66 functions as an interferon-stimulated gene (ISG) and hinders replication of various viruses including human immunodeficiency virus-1(HIV-1), hepatitis C virus, kunjin virus, chikungunya virus, and herpes simplex virus type 1.Increased expression of C19ORF66 is observed in human psoriatic skin compared to normal tissue.
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