Synonyms: Anti-Adenovirus E1B19K-binding protein B5; Anti-BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like; Anti-BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A; Anti-NIP3-like protein X; Anti-NIP3L
MDL Number: MFCD03096659
Storage: -20C
Application: Anti-BNIP3L antibody produced in rabbit, a Prestige Antibody, is developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org). Each antibody is tested by immunohistochemistry against hundreds of normal and disease tissues. These images can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. The antibodies are also tested using immunofluorescence and western blotting. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit sigma.com/prestige.
Biochem Physiol Actions: BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like is a protein encoded by the BNIP3L gene in humans. It is a tumor suppressor gene located at chromosome 8p21. It functions in promoting apoptosis by interacting with antiapoptotic proteins (such as Bcl-2, Bcl-x(L), E1B19K, Nix) and as a tumor suppressor. It is involved in lung cancer development and occurrence, when down-regulated.
Legal Information: Prestige Antibodies is a registered trademark of Sigma-Aldrich Co. LLC