Monoclonal Anti-ß-Tubulin I (mouse IgG1 isotype) is derived from the SAP.4G5 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from a BALB/c mouse. Tubulin is the major building block of microtubules, an intracellular cylindrical filamentous structure, that is present in almost all eukaryotic cells. Tubulin exists in all cells as a 100 kDa protein, which assembles from heterodimers of a-tubulin and ß-tubulin; both have a molecular weight of 55 kDa and share considerable homology.
Synonyms: Anti-TUBB
Storage: -20C
Application: Anti-beta-Tubulin I antibody, Mouse monoclonal has been used in:
•immunoblotting
•immunofluorescence
•immunohistochemistry
Biochem Physiol Actions: beta-Tubulin I is also useful in deducing the role that different tubulin isotypes play in nerve development, function or maintenance.