Synonyms: BCL-W; BCLW; KIAA0271
MDL No.: MFCD02095879
Storage: -20C
UNSPSC Code: 12352203
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General description: This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. (provided by RefSeq)
Immunogen: BCL2L2 (NP_004041.1, 1 a.a. ~ 193 a.a) full-length human protein.SequenceMATPASAPDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRTFSDLAAQLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQEWMVAYLETRLADWIHSSGGWAEFTALYGDGALEEARRLREGNWASVRTVLTGAVALGALVTVGAFFASK
Physical form: Solution in phosphate buffered saline, pH 7.4
RIDADR: NONH for all modes of transport