Anti-Band 3 antibody, Mouse monoclonal (mouse IgG2a isotype) is derived from the BIII-136 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mouse immunized with glycophorin B purified from human erythrocytes.
Synonyms: AE 1; Anion exchange protein 1; Anion exchanger 1; Band 3 anion transport protein; Solute carrier family 4 member 1
Storage: -20C
Application: Anti-Band 3 antibody, Mouse monoclonal may be used in immunoblotting and immunoprecipitation.
Biochem Physiol Actions: As a response to an oxidative stress, Band 3 protein forms clusters and clear damaged and aged RBCs from circulation. Enhanced band 3 protein clustering is implicated in RBC disorders such as hemolytic anemia, glucose-6-phosphate dehydrogenase (G6PD) deficiency, malaria and sickle-cell disease.