Synonyms: Anti-Aurora-C; Anti-Aurora/Ipl1-related kinase 3; Anti-Aurora/Ipl1/Eg2 protein 2; Anti-Serine/threonine protein kinase 13
Storage: -20C
UNSPSC Code: 12352203
General description: Chromosomal segregation during mitosis as well as meiosis is regulated by kinases and phosphatases. The Aurora kinases, members of the Ser/Thr protein kinase family, associate with microtubules during chromosome movement and segregation. Aurora kinase C may play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis. This protein is localized to centrosome from anaphase to cytokinesis. Expression is limited to testis in normal cells. Elevated expression levels are seen only in a subset of cancer cells such as HepG2, HuH7 and HeLa cells. Aurora-C expression is maximum at M phase.
Immunogen: AURORAC (Q9UQB9, 225-260)This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human Aurora-C.
Physical form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
RIDADR: NONH for all modes of transport
WGK Germany: nwg