Synonyms: ATG5 Antibody - Anti-ATG5 (N-terminal) antibody produced in rabbit; Atg5 Antibody; Anti-APG5; Anti-APG5L; Anti-ASP; Anti-ATG5 autophagy related 5 homolog (S. cerevisiae); Anti-Apoptosis-specific protein; Anti-Autophagy protein 5-like
MDL Number: MFCD09753847
Storage: -20C
Application: Rabbit anti-ATG5 has been used for immunofluorescence and chemiluminescent western blot analyses.
Biochem Physiol Actions: Atg5 (Apg5) is a 32 kDa protein that is required for autophagy. Atg5 is covalently modified by Atg12, a ubiquitin-like modifier. The Atg12-Atg5-Atg16 complex thus formed, localizes to autophagosome precursors and regulates autophagosome formation. Studies have reported that Atg5 fragment that is formed by calpain cleavage has pro-apoptotic properties.