Synonyms: Anti-Apolipoprotein O precursor antibody produced in rabbit; Anti-Protein FAM121B antibody produced in rabbit
Storage: -20C
Application: All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry. The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit sigma.com/prestige.
Biochem Physiol Actions: APOO (Apolipoprotein O) gene encodes a protein belonging to the apolipoprotein family of proteins that are mainly involved in the transport and metabolism of lipids. This 198-amino acid protein has been found in association with HDL, LDL and VLDL. It is characterized by the presence of a chondroitin sulfate chain and may play a role in protecting the myocardium against lipid accumulation in obese and diabetic patients. Increased levels of plasma apolipoprotein O has been observed in patients with acute coronary syndrome.
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