Synonyms: Anti-beta-2-Glycoprotein I antibody produced in rabbit; Anti-beta2-GPI antibody produced in rabbit; Anti-beta2-Glycoprotein 1 precursor antibody produced in rabbit; Anti-beta2-Glycoprotein I antibody produced in rabbit; Anti-APC inhibitor antibody produced in rabbit; Anti-Activated protein C-binding protein antibody produced in rabbit; Anti-Anticardiolipin cofactor antibody produced in rabbit; Anti-Apo-H antibody produced in rabbit; Anti-Apolipoprotein H antibody produced in rabbit; Anti-B2GPI antibody produced in rabbit
Storage: -20C
Application: All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry. The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit sigma.com/prestige.
Biochem Physiol Actions: Apolipoprotein H (APOH) is also known as B2GP1 (ß-2-glycoprotein I), BG and B2G1. It is a phospholipid-binding serum protein with anticoagulant properties. It influences binding of anticardiolipin antibodies to cardiolipin, may influence induction of these antibodies in animals and may play a role in anticardiolipin-mediated thrombosis. This gene acts as a cationic protein that helps in binding to negatively charged surfaces (such as apoptotic cells). It is a major autoantigen recognized by autoantibodies (aPL).
Legal Information: Prestige Antibodies is a registered trademark of Sigma-Aldrich Co. LLC