The gene ADAM2 (disintegrin and metalloproteinase domain-containing protein 2) is mapped to human chromosome 8p11. It belongs to the ADAM family of proteins. The protein is present in the testis. It protein has a disintegrin-like domain.
Synonyms: Anti-ADAM 2; Anti-CT15; Anti-Cancer/testis antigen 15; Anti-Disintegrin and metalloproteinase domain-containing protein 2; Anti-Fertilin subunit beta; Anti-PH-30; Anti-PH30; Anti-PH30-beta
MDL Number: MFCD02262895
Storage: -20C
Application: Anti-ADAM2 antibody produced in rabbit, a Prestige Antibody, is developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org). Each antibody is tested by immunohistochemistry against hundreds of normal and disease tissues. These images can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. The antibodies are also tested using immunofluorescence and western blotting. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit sigma.com/prestige.
Biochem Physiol Actions: ADAM2 (disintegrin and metalloproteinase domain-containing protein 2) is an integrin binding protein. Absence of ADAM2 in mice causes defects in sperm-egg binding. In addition, it helps in transfer of sperm from the uterus into the oviduct.
Legal Information: Prestige Antibodies is a registered trademark of Sigma-Aldrich Co. LLC