Synonyms: Anti-ABCB8; Anti-M-ABC1; Anti-MABC1; Anti-Mitochondrial ATP-binding cassette 1; ATP-binding cassette sub-family B member 8, mitochondrial
Storage: -20C
UNSPSC Code: 12352203
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General description: ABCB8 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC proteins are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. The function of this half-transporter has not yet been determined; however, it may involve the compartmentalization and transport of heme, as well as peptides, from the mitochondria to the nucleus and cytosol. The protein may also play a role in the transport of phospholipids into mitochondrial membranes.
Immunogen: ABCB8 (NP_009119, 26-62)This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human ABCB8.
Physical form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
RIDADR: NONH for all modes of transport
WGK Germany: nwg