The ACE gene codes for angiotensin-converting enzyme, which is one of the major enzymes in the RAS (renin angiotensin system). The ACE gene is localized on human chromosome 17q23.
Synonyms: ACE; ACE1; CD143; DCP; DCP1; Dipeptidyl carboxypeptidase I; Kininase II; Peptidyl-dipeptidase A; Peptidyldipeptide Hydrolase
Purity: >=95% (SDS-PAGE)
Storage: -20C
Biochem Physiol Actions: Angiotensin I converting enzyme (ACE) catalyzes the formation of angiotensin II from angiotensin I. It is a membrane-bound enzyme, which is expressed in atherosclerotic lesions. It plays an important role in the development of various diseases like systemic lupus erythematosus, hypertension, chronic kidney disease and diabetic nephropathy.