Primary Nav Button
GO

  • PRODUCT AVAILABILITY: Did you know you can view a product's availability right on the product page? Simply enter the quantity you want to purchase and the current availability will appear below the item.

  • This product requires a special fee, which will be shown on the Review page during Checkout.

MilliporeSigma

AN1 >=98% (HPLC)

Not yet rated

NOTE: Due to special handling or shipping requirements, these products will have additional fees added during checkout. Click HERE for a description of what fees might be charged.

AN1 >=98% (HPLC)

Synonyms: 5-Bromo-3-[(3-bromo-4,5-dihydroxyphenyl)methylene]-1,3-dihydro-2H-indol-2-one; mHTT-LC3 linker AN1

Molecular Formula: C15H9Br2NO3

Molecular Weight: 411.04

Linear Structural Formula: C15H9Br2NO3

Purity: >=98% (HPLC)

Storage: 2-8C

Biochem Physiol Actions: AN1 is a brain blood barrier penetrant agent that tether LC3 and mHTT and targets mHTT for autophagosome degradation. AN1 significantly lower mHTT in cortices of HD mice, in cells from patients with Huntington's disease, and neurons derived from induced pluripotent stem cells. AN1 does not lower wtHTT in fibroblasts from healthy human donors. It appears that AN1 interact with the polyQ stretch.

Please Enter Your Order Info

Filter by:

  • Clear Filters
Product Detail
Thomas No.
CHM02R117
Mfr. No.
SML2812-5MG
Description
SML2812-5MG, AN1 >=98% (HPLC)
CAS Number
486443-73-6
list price/quantitytotal
$0.00
Thomas No.
CHM02R118
Mfr. No.
SML2812-25MG
Description
SML2812-25MG, AN1 >=98% (HPLC)
CAS Number
486443-73-6
list price/quantitytotal
$0.00
$0.00 (0 Items)
Product is restricted and can only be purchased by customers with a web profile linked to a Thomas Business Account - Click here to login or create your web profile.

Write A Review

Submit Review
Cancel
Back To Top

About

Resources

Support

Shopping Tools

ISO 9001:2015 Certified Company
©Thomas Scientific 2026 All Rights Reserved.