Synonyms: Ampicillin trihydrate; D-(−)-α-Aminobenzylpenicillin
Formula: C16H19N3O4S · 3H2O
Formula Weight: 403.45
CAS No.: 7177-48-2
Storage Temperature: 2-8°C
Application: Used to select for ampicillin resistance in mutated and transformed cells.
Biochem/physiol Actions: A β-lactam antibiotic with an amino group side chain attached to the penicillin structure. Penicillin derivative that inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Bactericidal only to growing Escherichia coli . Mode of resistance: Cleavage of β-lactam ring of ampicillin by β-lactamase. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.