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MilliporeSigma

Amoxicillin trihydrate: potassium clavulanate (4:1)

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Amoxicillin trihydrate is a semisynthetic antibiotic, that is used as a medicine.

Synonyms: Amoxicillin Trihydrate: Potassium Clavulanate

Storage: 2-8C

Application: Amoxicillin trihydrate: potassium clavulanate (4:1) has been used to study its effect on the viral déjà vu disease (neonatal intracerebral (i.c.) infection) in mice model.

Biochem Physiol Actions: Amoxicillin trihydrate is a broad-spectrum, ß-lactam antibiotic. It inhibits the cross-linkage between linear peptidoglycan polymer chains that are the major component of both Gram-positive and Gram-negative bacteria. Since amoxicillin is degraded by ß-lactamases, it does not show activity against bacteria which produce these enzymes.Clavulanate is a ß-lactam antibiotic related to the penicillins. Clavulanate competitively and irreversibly inhibits a wide variety of ß-lactamases found in bacteria that are resistant to penicillins and cephalosporins.Formulations of amoxicillin with clavulanic acid prevent the degradation of amoxicillin by ß-lactamase enzymes. This increases amoxicillin's antibacterial activity against bacteria normally resistant to ß-lactam antibiotics.

Other Notes: Keep container tightly closed in a dry and well-ventilated place. Never allow product to get in contact with water during storage.

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Thomas No.
CHM01W000
Mfr. No.
SMB00607-1G
Description
SMB00607-1G Amoxicillin trihydrate: potassium clavulanate (4:1)
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