Synonyms: ADL-8-2698; LY-246736; N-[(2S)-2-[[(3R,4R)-4-(3-Hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl]-1-oxo-3-phenylpropyl]glycine
Molecular Formula: C25H32N2O4
Molecular Weight: 424.53
Linear Structural Formula: C25H32N2O4
MDL Number: MFCD09838268
Purity: >=98% (HPLC)
Storage: 2-8C
Biochem Physiol Actions: Alvimopan is a gastroprokinetic peripheral mu-opioid receptor antagonist. As a drug, Alvimopan is given to patients undergoing bowel surgery to protect the bowel from the effects of opioid medications that are used to treat pain, blocking the undesirable GI side-effects of the opioid agonists without affecting analgesia or causing withdrawal. Alvimopan does not cross the blood-brain barrier, competitively binding to gastrointestinal tract mu-opioid receptors.