Synonyms: (2S,4S,5S,7S)-N-(2-Carbamoyl-2-methylpropyl)-5-amino-4-hydroxy-2,7diisopropyl-8-[4-methoxy-3-(3-methoxypropoxy)phenyl]-octanamide hemifumarate; CGP-60536; CGP60536B; Rasilez; SPP-100
Molecular Formula: C30H53N3O6 · 0.5 C4H4O4
Molecular Weight: 609.79
Linear Structural Formula: C30H53N3O6 · 0.5 C4H4O4
MDL Number: MFCD27756642
Purity: >=95% (HPLC)
Storage: -20C
Biochem Physiol Actions: Aliskiren is a potent nonpeptide direct renin inhibitor with an IC50 value of 0.6 nM. It has antihypertensive activity, decreasing plasma renin activity and inhibiting the conversion of angiotensinogen to Angiotensin I by binding to the S3 sub-pocket of renin.