P(t-Bu)3 Pd G2 (Chloro[(tri-tert-butylphosphine)-2-(2-aminobiphenyl)] palladium(II)) is a second generation (G2) precatalyst containing a biphenyl-based ligand. Product participates in various palladium catalyzed cross-coupling reactions, C-C, C-N and C-O bond formation reactions, and Suzuki-Miyaura coupling reactions. It generates active Pd catalyst at room temperature in the presence of weak phosphate or carbonate bases. It has been proposed as an active catalyst for use in Stille reactions of aryl halides (bromides and chlorides).
Synonyms: Chloro[(tri-tert-butylphosphine)-2-(2-aminobiphenyl)] palladium(II)
Molecular Formula: C24H37ClNPPd
Molecular Weight: 512.4
Linear Structural Formula: C24H37ClNPPd
MDL Number: MFCD21608496
Melting Point: 167-170 C (decomposition)
Application: P(t-Bu)3 Pd G2 (Chloro[(tri-tert-butylphosphine)-2-(2-aminobiphenyl)] palladium(II), Pd/P(t-Bu)3) may be used as catalyst in the following studies:
•Synthesis of sterically hindered biaryls (tetra-ortho-substituted), via cross-coupling reactions of aryl chlorides.
•Stille cross-couplings reactions of aryl chloride.
•Synthesis of chloropeptin I, via Stille cross-coupling reaction.
•Heck reaction.
•Negishi cross-coupling reactions.