Synonym(s): Dimethylformiminium chloride; Eschenmoser's salt; Methylenedimethylammonium chloride
Formula: CH2=N+(CH3)2Cl-
Formula Weight: 93.56
CAS No.: 30354-18-8
UN Number: UN1325
Purity: ≥95.0% (AT)
Application: Reacant for:
Preparation of dihydronaphthyridinones as HIV-1 integrase inhibitors
Mannich reactions
Preparation of cyanotetrahydrooxo-ß-carbolines via cyclocondensation reactions
Asymmetric synthesis of phalarine via stereospecific Pictet-Spengler cyclocondensation and traceless chirality transfer from L-tryptophan
Synthesis of functionalized diarylpyrrolizines as inhibitors of microsomal prostaglandin E2 synthase-1 (mPGES-1) and 5-lipoxygenase (5-LOX)
Synthesis of (±)-phalarine with the rearrangement of an azaspiroindolenine and Gassman oxindole preparation as key steps
Other Notes: "Mannich-reagent" for direct use; higher yields of purer products were achieved in shorter times compared with the classical "Mannich reaction"7,8,9; in-situ preparation of the reactive triflate with TMS-triflate10
Packaging: 5, 25 g in glass bottle
Beilstein Registry Number: 505955
EC No.: 250-142-4
Melting Point: 146-148°C(lit.)
Empirical Formula (Hill Notation): C72H60P4Pd