Synonyms: 2-Chloro-N-(2-chloroethyl)-N-methylethanamine; N-Methylbis(2-chloroethyl)amine hydrochloride; Bis(2-Chloroethyl)methylamine; Bis(2-chloroethyl)methylamine; MBA hydrochloride; NM; Nitrogen mustard
CAS Number: 55-86-7
Formula: C5H11Cl2N · HCl
Formula Weight: 192.51
Linear Formula: (ClCH2CH2)2NCH3·HCl
MDL No.: MFCD00012517
Purity: 0.98
Melting Point: 108-111 C (lit.)
EC Number: 200-246-0
UNSPSC Code: 12352100
Application: Mechlorethamine hydrochloride was used in a fluorescence-based apurinic/apyrimidinic site cleavage assay for the identification of apurinic/apyrimidinic endonuclease inhibitors in human cells. It was used in a study to demonstrate the effect of povidone iodine ointment against skin toxicity caused by sulphur and nitrogen mustard.
Biochem/physiol Actions: Mechlorethamine hydrochloride administration reduces the tensile strength of the abdominal wounds in rats.
RTECS: IA2100000
RIDADR: UN 2928 8(6.1) / PGII
WGK Germany: 3
R Codes: 45-46-61-27/28-34
S Codes: 53-36/37/39-45
IOD Codes: T+
Symbol: GHS05, GHS06, GHS08
Signal Word: Danger
Hazard Statements: H300 + H310-H314-H340-H350-H360D
Precautionary statements: P201-P264-P280-P301 + P310-P302 + P350-P305 + P351 + P338