Lysine is a basic ketogenic amino acid with a protonated alkyl amino group. Lysine degradation results in the formation of acetoacetate. Acetylation/deacetylation of lysine residues in histones is a mechanism to regulate chromatin organization in eukaryotes. Isotope labeled amino acids are required for the production of isotopically labeled proteins.
Synonyms: SILAC Amino Acid; (S)-2,6-Diaminohexanoic acid-13C6,15N2 hydrochloride; 13C and 15N Labeled Lys; 13C and 15N Labeled lysine hydrochloride
Molecular Formula: 13C6H15Cl15N2O2
Molecular Weight: 190.59
Linear Structural Formula: H215N(13CH2)413CH(15NH2)13CO2H · HCl
MDL Number: MFCD00144647
Purity: 95% (CP)
Melting Point: 263-264 C (dec.) (lit.)
Application: Pulsed Stable Isotope labeling of amino acid has been used to study host-cell function, survival, the precise intracellular pathways in protein synthesis of HIV-1 infected human monocytederived macrophages.