CAS Number: 868-85-9
Formula: C2H7O3P
Formula Weight: 110.05
Linear Formula: (CH3O)2P(O)H
MDL No.: MFCD00044633
Purity: 0.98
Boiling Point: 170-171 C(lit.)
Density: 1.2 g/mL at 25 C(lit.)
Refractive Index: n20/D 1.402(lit.)
Beilstein Registry Number: 1697490
EC Number: 212-783-8
UNSPSC Code: 12352100
Application: Dimethyl phosphite is used in the synthesis of α-aminophosphonates, which are medicinally important phosphorus analogs of amino acids, by treating with an amine and an aldehyde or a ketone. It can also be employed in asymmetric hydrophosphonylation of aldehydes to synthesize optically active α-hydroxy phosphonates.
Application: Dimethyl phosphite may be used as an effective alternative to organic tin hydrides as radical reducing agents for organic halides, thionoesters, and isocyanides to form the corresponding hydrocarbons. Radical translocation/cyclization reactions of terminal alkynes to form cyclic phosphonates can also be effectively carried using dimethyl phosphite as a reagent under tin-free condition.
RTECS: SZ7710000
RIDADR: UN 3278 6.1 / PGIII
WGK Germany: 1
Flash Point(F): 158 F
Flash Point(C): 70 C
R Codes: 40-43-52/53-68
S Codes: 36/37-61
IOD Codes: Xn
Symbol: GHS07, GHS08
Signal Word: Warning
Hazard Statements: H317-H341-H351-H412
Precautionary statements: P273-P280