Synonym(s): DTBP; Dimethyl 3,3′-dithio-bis(propionimidate) dihydrochloride; Wang/Richards' reagent
Formula: C8H16N2O2S2 · 2HCl
Formula Weight: 309.28
CAS No.: 38285-78-8
Application: Reactant for:
• Synthesis of glutathione-sensitive cross-linked polyethylenimine gene vector
• Preparation of cyclodextrin-containing polymers designed for gene delivery
• Crosslinking of chick oviduct progesterone-receptor subunits
Other Notes: Note that the amidine linkage preserves original primary amine positive charge. The disulfide linkage is cleavable by mild reduction. Incorporates an eight atom linker.
Caution: The reagant is readily hydrolyzed at neutral pH. Avoid use of reducing agents during coupling reactions.
Storage: 2-8°C
Packaging: 100 mg in poly bottle
Empirical Formula (Hill Notation): C7H9BO3