Synonym(s): DBCO-PEG4-maleimide
Formula: C36H42N4O9
Formula Weight: 674.74
Purity: 98% (HPLC)
Application: Maleimide functionalized cyclooctyne derivative for incorporation of the cyclooctyne moiety into thiol containing compounds or biomolecules. Cyclooctynes are useful in strain-promoted copper-free azide-alkyne cycloaddition reactions. This dibenzocyclooctyne will react with azide functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage. The PEG lipophilic spacer helps to reduce aggregation and precipitation problems when labeling biomolecules.
Applications Include:
• Protein-peptide conjugates
• Antibody-enzyme or antibody-drug conjugates
• Protein or peptide-oligonucleotide conjugates
• Surface modification
Storage: −20°C
Packaging: 1, 5, 50 mg in glass bottle
Empirical Formula (Hill Notation): C3H10N2O