Synonym(s): N-(4-Pyridylmethylene)-tert-butylamine N,N′-dioxide; N-tert-Butyl-α-(4-pyridyl)nitrone N′-oxide; POBN
Formula: C10H14N2O2
Formula Weight: 194.23
CAS No.: 66893-81-0
Purity: 99%
Application: Spin trap reagent used to measure ethanol oxidation to 1-hydroxyethyl radical (HER) which can bind to protein. Has also been used in studies of DNA methylation, iron-mediated polyunsaturated fatty acid peroxidation, and free-radical formation by Alzheimer β-amyloid peptide. The formation of hydroxyl radical in chondrocytes and cartilage has been detected using POBN.
Packaging: 1 g in glass bottle
Beilstein Registry Number: 1453764
EC No.: 266-512-3
Melting Point: 183-185°C(lit.)
Empirical Formula (Hill Notation): C15H14O3