Synonym(s): Indol-6-ylamine; NSC 82379
Formula: C8H8N2
Formula Weight: 132.16
CAS No.: 5318-27-4
Purity: 97%
Application: Reactant for preparation of:
• Inhibitors of mammalian target of rapamycin (mTOR ) protein
• Inhibitors of the AcrAB-TolC efflux pump
• Inhibitors of Gli1-mediated transcription in the Hedgehog pathway
• Potent DNA-topoisomerase II poisons and anti-MDR agents
• Protein kinase C θ (PKCθ) inhibitors
• Piperidine carboxamide as transient receptor potential cation channel subfamily V member 1 (TRPV1) antagonists
• Potent and selective blockers of the Nav1.8 sodium channel as potential analgesics for the treatment of neuropathic and inflammatory pain
• 5,6-fused heteroaromatic ureas as TRPV1 antagonists
• Allosteric enhancers of the A3 adenosine receptor
• Human liver glycogen phosphorylase (HLGP) inhibitors for the treatment of type 2 diabetes
Storage: −20°C
Packaging: 1, 5 g in glass bottle
Melting Point: 75-79°C
Empirical Formula (Hill Notation): C2H3Br3O