Synonyms: Tetramethylene chlorohydrin
CAS Number: 928-51-8
Formula: C4H9ClO
Formula Weight: 108.57
Linear Formula: HO(CH2)4Cl
MDL No.: MFCD00002967
Purity: ~85%
Boiling Point: 84-85 C/16 mmHg(lit.)
Density: 1.088 g/mL at 25 C(lit.)
Refractive Index: n20/D 1.453(lit.)
Storage: 2-8C
Beilstein Registry Number: 1731408
UNSPSC Code: 12352100
General description: 4-Chloro-1-butanol, an alkylating agent, is one of the genotoxic impurity in active pharmaceutical ingredients. Reaction of 4-chloro-1-butanol and Reichardt′s dye has been monitored spectrophotometrically for the determination of genotoxic impurities in pharmaceuticals.
Application: 4-Chloro-1-butanol was employed as an internal standard in the analysis of genotoxic impurities in active pharmaceutical ingredients by GC-MS technique.
Other Notes: Contains tetrahydrofuran and HCl
RIDADR: UN 2924 8(3) / PGIII
WGK Germany: 3
Flash Point(F): 96.8 F
Flash Point(C): 36 C
R Codes: 10-19-22-36/37/38-40
S Codes: 26-36/37-60
IOD Codes: Xn
Symbol: GHS02, GHS05, GHS07, GHS08
Signal Word: Warning
Hazard Statements: H226-H290-H302-H315-H319-H335-H351
Precautionary statements: P210-P280-P301 + P312 + P330-P305 + P351 + P338-P370 + P378