Synonym(s): 5-(Triphenylphosphonio)pentanoic acid bromide; Carboxybutyltriphenylphosphonium bromide; NSC 147756
Formula: (C6H5)3P(Br)(CH2)4COOH
Formula Weight: 443.31
CAS No.: 17814-85-6
Purity: 98%
Application: • Used as a platform for delivery of pro-apoptotic peptides into the mitochondria of tumor cells
Reactant for preparation of:
• Ring skeletons via ring closing metathesis and double bond migration ring closing metathesis reactions
• Methyl alkenyl quinolones as antimycobacterial agents
• Prostaglandins and their drug analogs via Gold-catalyzed Meyer-Schuster rearrangement
• Diphenylmethylpiperazines as N-type calcium channel blockers as potential therapeutic agents
• Folate receptor-specific glycinamide ribonucleotide formyltransferase (GARFTase) inhibitors with antitumor activity
• Cycloalkylidene alkanols with antileishmanial activity, via Wittig reaction
Packaging: 10, 50, 250 g in poly bottle
Beilstein Registry Number: 3586477
EC No.: 241-782-5
Melting Point: 204-207°C(lit.)
Empirical Formula (Hill Notation): C10H17NO4