Synonyms: (2-Chloromethoxyethyl)trimethylsilane; Chloromethyl 2-trimethylsilylethyl ether; SEM-Cl; SEM-chloride
CAS Number: 76513-69-4
Formula: C6H15ClOSi
Formula Weight: 166.72
Linear Formula: (CH3)3SiCH2CH2OCH2Cl
MDL No.: MFCD00009919
Boiling Point: 170-172 C(lit.); 57-59 C/8 mmHg(lit.)
Density: 0.942 g/mL at 25 C(lit.)
Refractive Index: n20/D 1.435(lit.)
Storage: 2-8C
Beilstein Registry Number: 3587289
EC Number: 278-483-4
UNSPSC Code: 12352000
Features and Benefits: Convenient hydroxyl-protecting reagent. SEM-ethers are stable over a wide pH range, and can be selectively cleaved with fluoride ion under mild aprotic conditions.
General description: Learn More at the Professor and Product Portal of Professor Bruce Lipshutz.
Application: Used to prepare a SEM-ether which was, in turn, removed with BBr3 and cyclized to a benzo-oxapane.
Application: Phenol protecting group in the synthesis of laterifluorones.
RIDADR: UN 2920 3(8) / PGII
WGK Germany: 3
Flash Point(F): 114.8 F
Flash Point(C): 46 C
R Codes: 12693
S Codes: 26-28-36/37/39-45
IOD Codes: C
Symbol: GHS02, GHS05
Signal Word: Danger
Hazard Statements: H226-H314
Precautionary statements: P280-P305 + P351 + P338-P310