Synonym(s): 1-Methyl-4-(pentafluorophenyl)-2-(diphenylphosphino)-1,4-benzenedicarboxylate
Formula: C27H16F5O4P
Formula Weight: 530.38
Purity: 97%
Application: • Staudinger ligation reagent for the conjugation of amine and azide containing compounds or biomolecules.
• The amine functionalized molecule first reacts with the phosphine through the activated pentafluorophenyl ester.The azide-molecule is then reacted with the newly labeled phosphine to form the iminophosphorane, and the aza-ylide is subsequently captured by the methyl ester to yield the covalent conjugated product.
The Staudinger Ligation: A High-Yield, Chemoselective, and Mild Synthetic Method
Storage: −20°C
Packaging: 25, 100 mg in glass bottle
Melting Point: 109-111°C
Empirical Formula (Hill Notation): C7H5NO2