Synonyms: N,N-Dimethyl-2-hydroxyethylamine; N,N-Dimethylethanolamine; DMEA; Jeffcat DMEA
CAS Number: 108-01-0
Formula: C4H11NO
Formula Weight: 89.14
Linear Formula: (CH3)2NCH2CH2OH
MDL No.: MFCD00002846
Purity: >=99.5%
Boiling Point: 134-136 C(lit.)
Melting Point: -70 C (lit.)
Density: 0.886 g/mL at 20 C(lit.)
Refractive Index: n20/D 1.4294(lit.)
Beilstein Registry Number: 1209235
EC Number: 203-542-8
UNSPSC Code: 12352100
General description: 2-Dimethylaminoethanol (DMAE/deanol) is an amino alcohol. It is the main product formed during the amination of ethylene glycol by dimethylamine on alumina supported copper in a continuous fixed-bed reactor. DMAE has been reported to be the putative precursor of acetylcholine. Its effect as a skin-firming and anti-wrinkle agent has been studied. Microwave spectrum of 2-dimethylaminoethanol has been investigated. Its effect as an organic additive on deposition and anti-reflective properties of porous CaF2 has been studied. Removal of the benzyl ester groups by transesterification with 2-dimethylaminoethanol from benzyl protected tripeptides has been reported.
Application: 2-Dimethylaminoethanol (deanol) may be used as a ligand in the copper-catalyzed amination of aryl bromides and iodides.2-Dimethylaminoethanol (deanol, DMAE, DMEA) may be used in the synthesis of the following:. cis -[Co(sac)2(dmea)2] and cis -[Zn(sac)2(dmea)2] (sac=saccharinate). heterotrinuclear complex [Cu2Zn(NH3)I3(Me2Ea)3 (HMe2Ea=2-dimethylaminoethanol). 2-alkoxy-N,N-dimethylethylamine. mixed-metal complexes of copper(II) and lead(II)
RTECS: KK6125000
RIDADR: UN 2051 3(8) / PGII
WGK Germany: 1
Flash Point(F): 102.2 F
Flash Point(C): 39 C
R Codes: 10-20/21/22-34
S Codes: 25-26-36/37/39-45
IOD Codes: C
Symbol: GHS02, GHS05, GHS06
Signal Word: Danger
Hazard Statements: H226-H302 + H312-H314-H331
Precautionary statements: P261-P280-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338-P370 + P378