Synonym(s): Metformin
Formula: NH2C(=NH)NHC(=NH)N(CH3)2 · HCl
Formula Weight: 165.62
CAS No.: 1115-70-4
Purity: 97%
Packaging: 5 g in glass bottle
EC No.: 214-230-6
Melting Point: 223-226°C(lit.)
Biochem/physiol Actions: Metformin is an antidiabetic agent that reduces blood glucose levels and improves insulin sensitivity. Its metabolic effects, including the inhibition of hepatic gluconeogenesis, are mediated at least in part by activation of the LKB1-AMPK (AMP-activated protein kinase) pathway. Activation of this pathway also appears to be involved in the antiproliferative and proapoptotic actions of metformin in cancer cell lines.
Empirical Formula (Hill Notation): C4H3BrO