Synonyms: 1-[2-(1-Adamantyl)ethoxy]-3-(3,4-dihydro-2(1H)-isoquinolinyl)-2-propanol hydrochloride; 3,4-Dihydro-alpha-[(2-tricyclo[3.3.1.13,7]dec-1-ylethoxy)methyl]-2(1H)-isoquinolineethanol hydrochloride
Molecular Formula: C24H35NO2 · HCl
Molecular Weight: 406.0
Linear Structural Formula: C24H35NO2 · HCl
Purity: >=98% (HPLC)
Storage: 2-8C
Biochem Physiol Actions: ADDA 5 is a potent and selective inhibitor of cytochrome c oxidase (Complex IV) that depletes the bioenergetics reserve capacity in intact glioma cells. ADDA 5 specifically inhibits the proliferation of chemosensitive and chemoresistant glioma cells, while sparing non-cancer cells. Additionally ADDA 5 is effective against glioma stem cells.