Synonyms: 5-[3,5-Bis(trifluoromethyl)phenyl]-1H-tetrazole Solution; 5-[3,5-Bis(trifluoromethyl)phenyl]-2H-tetrazole Solution; Activator 42(R) Solution
Purity: 70-77 g/L (Activator 42 content, titration)
Legal Information: This product and it use is are covered under US Patent Number 7,897,758
Other Notes: Activator solution, containing 5-(3,5-bis(trifluoromethyl)phenyl)-1H-tetrazole (Activator 42) in acetonitrile, are mixed with solutions of phosphoramidites during the extension step. The activator reacts with the amidite group to form a highly reactive intermediate. The intermediate then forms an internucleotide bond with the detritylated 5′hydroxyl group of the growing oligonucleotide chain.