Synonym: ACh
CAS Number: 60-31-1
Linear Formula: (CH3)3N+CH2CH2OCOCH3Cl-
Molecular Weight: 181.66
Beilstein Registry Number: 3571875
EC Number: 200-468-8
MDL Number: MFCD00011698
PubChem Substance ID: 24891113
Caution
Very hygroscopic
Packaging
10 mg in autosample vial; 25, 100, 500 g in glass bottle
Biochem/physiol Actions
Acetylcholine chloride, injected at 20 mg/kg body weight, reduces mortality and plasma proinflammatory cytokines in mice with experimentally-induced sepsis 1. The cholinergicanti-infl ammatory mechanism is probably mediated by interaction of acetylcholine with α7n cholinoreceptor on monocytes, macrophages, and neutrophils, which decreases the levels of proinflammatory cytokines such as TNF-α, IL-1β, and IL-6.
Assay: ≥99% (TLC)
MP: 146-150 °C(lit.)
Solubility: H2O: soluble100 mg/mL