The Accuris GenoSep™ is a compact capillary electrophoresis system for high-resolution nucleic acid and protein characterization. The system combines automated capillary electrophoresis with sensitive fluorescence detection to deliver accurate fragment sizing, quantification, and quality assessment for DNA, RNA, proteins, NGS libraries, and cell-free DNA (cfDNA) samples. The Accuris GenoSep™ instrument utilizes convenient, reusable cartridges to separate nucleic acids and proteins. Each cartridge incorporates a proprietary polymer matrix and a fused silica capillary. During analysis, programmable high voltage is applied through the capillary to generate an electric field that drives the electrophoretic migration of macromolecules through the polymer matrix. Differences in electrophoretic mobility result in size-based separation, and fluorescently labeled fragments are detected as they pass the optical detection window. User-selectable voltages enable methods to be optimized for different applications and fragment size ranges. Figure 1 displays HeLa RNA separation using GenoSep.