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MilliporeSigma

AC1903 >=98% (HPLC)

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AC1903 >=98% (HPLC)

Synonyms: N-(2-Furanylmethyl)-1-(phenylmethyl)-1H-benzimidazol-2-amine

Molecular Formula: C19H17N3O

Molecular Weight: 303.36

Linear Structural Formula: C19H17N3O

MDL Number: MFCD06609959

Purity: >=98% (HPLC)

Storage: 2-8C

Biochem Physiol Actions: AC1903 is a specific inhibitor of TRPC5, the transient receptor potential canonical channel 5, a Ca2+ permeable nonselective cation channel highly expressed in brain and kidney. AC1903 did not inhibit TRPC4 or TRPC6 currents and showed no off-target effects in kinase profiling assays. It specifically blocked TRPC5 channel activity in glomeruli of proteinuric rats, suppressed severe proteinuria, showing a therapeutic benefit in a rat model of hypertensive proteinuric kidney disease.

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Product Detail
Thomas No.
CHM02U589
Mfr. No.
SML2244-5MG
Description
SML2244-5MG, AC1903 >=98% (HPLC)
CAS Number
831234-13-0
list price/quantitytotal
$0.00
Thomas No.
CHM02U590
Mfr. No.
SML2244-25MG
Description
SML2244-25MG, AC1903 >=98% (HPLC)
CAS Number
831234-13-0
list price/quantitytotal
$0.00
$0.00 (0 Items)
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