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MilliporeSigma

A01 (Smurf1 inhibitor) >=98% (HPLC)

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A01 (Smurf1 inhibitor) >=98% (HPLC)

Synonyms: [4-[[4-Chloro-3-(trifluoromethyl)phenyl]sulfonyl]-1-piperazinyl][4-(5-methyl-1H-pyrazol-1-yl)phenyl]methanone

Molecular Formula: C22H20ClF3N4O3S

Molecular Weight: 512.93

Linear Structural Formula: C22H20ClF3N4O3S

MDL Number: MFCD09320899

Purity: >=98% (HPLC)

Storage: 2-8C

Biochem Physiol Actions: A01 is a high affinity selective inhibitor of E3 ubiquitin-protein ligase Smurf1 (Smad ubiquitination regulatory factor-1) that disturbs Smurf1-Smad1/5 interaction and blocks Smurf1 mediated Smad1/5 ubiquitination. A01 increases responsiveness to BMP-2 in myoblasts and osteoblasts.

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Product Detail
Thomas No.
CHM02J114
Mfr. No.
SML1404-5MG
Description
SML1404-5MG, A01 (Smurf1 inhibitor) >=98% (HPLC)
CAS Number
1007647-73-5
list price/quantitytotal
$0.00
Thomas No.
CHM02J115
Mfr. No.
SML1404-25MG
Description
SML1404-25MG, A01 (Smurf1 inhibitor) >=98% (HPLC)
CAS Number
1007647-73-5
list price/quantitytotal
$0.00
$0.00 (0 Items)
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