Synonyms: (3S,4R)-1-Benzyl-N,N-dimethyl-4-(4-(4-(methylsulfonyl)piperazin-1-yl)phenyl)pyrrolidin-3-amine; (3S,4R)-{1-Benzyl-4-[4-(4-methanesulfonyl-piperazin-1-yl)-phenyl]-pyrrolidin-3-yl}-dimethyl-amine
Molecular Formula: C24H34N4O2S
Molecular Weight: 442.62
Linear Structural Formula: C24H34N4O2S
Purity: >=98% (HPLC)
Storage: 2-8C
Biochem Physiol Actions: A-395N is a control probe for A-395, which is a chemical probe for polycomb protein EED. A-395 is a potent and selective chemical probe for the polycomb protein EED (embryonic ectoderm development), an essential component of Polycomb repressive complex 2 (PRC2), involved in transcriptional repression through methylation of histone H3K27. A-395N is structurally similar, but exhibits no activity in the biochemical and cellular assays, so is an ideal control compound. For characterization details of the active probe, A-395, please visit the A-395 probe summary on the Structural Genomics Consortium (SGC) website.A-395, the active enantiomer, is available from Sigma. To learn more about and purchase A-395, click here.To learn about other SGC chemical probes for epigenetic targets, visit sigma.com/sgc