Synonyms: 2,8-Diamino-1,9-dihydro-6H-purin-6-one; 2,8-Diamino-hypoxanthine; NSC 23170
Molecular Formula: C5H6N6O
Molecular Weight: 166.14
Linear Structural Formula: C5H6N6O
Purity: >=95% (HPLC)
Storage: 2-8C
Biochem Physiol Actions: 8-Aminoguanine, a guanine derivative, is an orally available and highly efficacious potassium-sparing diuretic/natriuretic that increased sodium excretion by 17.2-fold and decrease potassium excretion by 71.0%. 8-Aminoguanine increases glucose excretion by 12.1-fold. Also, 8-Aminoguanine suppressed deoxycorticosterone/salt-induced hypertension.