Synonyms: EdU
Molecular Formula: C11H12N2O5
Molecular Weight: 252.22
Linear Structural Formula: C11H12N2O5
Purity: 95%
Melting Point: 206 C
Storage: -20C
Application: 5-Ethynyl-2'-deoxyuridine (EdU) is a thymidine analog that can be incorporated into replicating DNA for detection of cell proliferation. It has an alkyne handle that can ligate with azide-containing fluorescent probes through a highly efficient click chemistry reaction. EdU nucleoside can be incorporated into the DNA of cells either in culture or in animals without showing significant toxicity. The assay offers a simpler workflow for detecting cell proliferation than anti-BrdU assays.For information on Baseclick kits containing all the reagents for the assays see: Baseclick kitsFor a listing of the Baseclick kits see: Baseclick kits