Synonym: 5-BrdU, 5-Bromo-1-(2-deoxy-β-D-ribofuranosyl)uracil, 5-Bromouracil deoxyriboside, BUdR
Empirical Formula (Hill Notation): C9H11BrN2O5
Molecular Weight: 307.10
Beilstein Registry Number: 30395
EC Number: 200-415-9
MDL Number: MFCD00006529
PubChem Substance ID: 24278270
Biochem/physiol Actions
Thymidine analog used as a mutagen in genetic research. Selectively incorporated into cellular DNA during S-phase.
Packaging
1, 5, 100 g in glass bottle; 100, 250, 500 mg in glass bottle
Application
5-Bromo-2′-deoxyuridine (5-BrdU) is a thymidine analogue which is incorporated into DNA. 5-BrdU is routinely and extensively used to measure DNA synthesis and to label dividing cells. Consequently 5-BrdU is used to study cell signaling and other processes that induce cell proliferation.
Assay: ≥99% (HPLC)
MP: 191-194 °C (dec.)(lit.)
Storage Temp.: −20°C