Synonyms: (4-Acetamidophenyl)(fluorosulfonyl)sulfamoyl fluoride; AISF
Molecular Formula: C8H8F2N2O5S2
Molecular Weight: 314.29
Linear Structural Formula: C8H8F2N2O5S2
Purity: >=98%
Melting Point: 146-149 C
Application: 4-(Acetylamino)phenyl]imidodisulfuryl difluoride (AISF) is a shelf-stable, crystalline reagent for synthesis of fluorosulfates and sulfamoyl fluorides via reaction with phenol and amine nucleophiles. A convenient alternative to the toxic sulfuryl fluoride gas traditionally required for installation of the valuable -SO2F functional group, the solid reagent AISF will find wide utility in preparation of synthetic precursors as well as chemical biology, polymer chemistry, cross-coupling, and deoxyfluorination applications. This product was introduced collaboratively with Pfizer and BioDuro.
Other Notes: Introduction of a Crystalline, Shelf-Stable Reagent for the Synthesis of Sulfur(VI) FluoridesTechnology Spotlight